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Mycobacterium tuberculosis-Specific T Cell Functional, Memory, and Activation Profiles in QuantiFERON-Reverters Are Consistent With Controlled Infection

Reversion of immune sensitization tests for Mycobacterium tuberculosis (M.tb) infection, such as interferon-gamma release assays or tuberculin skin test, has been reported in multiple studies. We hypothesized that QuantiFERON-TB Gold (QFT) reversion is associated with a decline of M.tb-specific func...

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Detalles Bibliográficos
Autores principales: Mpande, Cheleka A. M., Steigler, Pia, Lloyd, Tessa, Rozot, Virginie, Mosito, Boitumelo, Schreuder, Constance, Reid, Timothy D., Bilek, Nicole, Ruhwald, Morten, Andrews, Jason R., Hatherill, Mark, Little, Francesca, Scriba, Thomas J., Nemes, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435731/
https://www.ncbi.nlm.nih.gov/pubmed/34526988
http://dx.doi.org/10.3389/fimmu.2021.712480