Insulin-like growth factor-2 does not improve behavioral deficits in mouse and rat models of Angelman Syndrome

BACKGROUND: Angelman Syndrome (AS) is a rare neurodevelopmental disorder for which there is currently no cure or effective therapeutic. Since the genetic cause of AS is known to be dysfunctional expression of the maternal allele of ubiquitin protein ligase E3A (UBE3A), several genetic animal models...

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Detalles Bibliográficos
Autores principales: Berg, Elizabeth L., Petkova, Stela P., Born, Heather A., Adhikari, Anna, Anderson, Anne E., Silverman, Jill L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444390/
https://www.ncbi.nlm.nih.gov/pubmed/34526125
http://dx.doi.org/10.1186/s13229-021-00467-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444390/
https://www.ncbi.nlm.nih.gov/pubmed/34526125
http://dx.doi.org/10.1186/s13229-021-00467-1

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