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Apoptosis-inducing activity of synthetic hydrocarbon-stapled peptides in H358 cancer cells expressing KRAS(G12C)

Lung cancers are the leading cause of cancer deaths worldwide and pose a grave threat to human life and health. Non-small cell lung cancer (NSCLC) is the most frequent malignancy occupying 80% of all lung cancer subtypes. Except for other mutations (e.g., KRAS(G12V/D)) that are also vital for the oc...

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Detalles Bibliográficos
Autores principales: Li, Cuicui, Zhao, Ni, An, Luyan, Dai, Zhen, Chen, Xiaoyi, Yang, Fan, You, Qidong, Di, Bin, Hu, Chi, Xu, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463269/
https://www.ncbi.nlm.nih.gov/pubmed/34589388
http://dx.doi.org/10.1016/j.apsb.2021.06.013