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Neuroprotective Effect of 1,4-Naphthoquinones in an In Vitro Model of Paraquat and 6-OHDA-Induced Neurotoxicity

Targeted screening using the MTT cell viability test with a mini-library of natural and synthetic 1,4-naphthoquinones and their derivatives was performed in order to increase the survival of Neuro-2a neuroblastoma cells in in vitro paraquat and 6-hydroxydopamine models of Parkinson’s disease. As a r...

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Detalles Bibliográficos
Autores principales: Menchinskaya, Ekaterina, Chingizova, Ekaterina, Pislyagin, Evgeny, Likhatskaya, Galina, Sabutski, Yuri, Pelageev, Dmitry, Polonik, Sergei, Aminin, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468277/
https://www.ncbi.nlm.nih.gov/pubmed/34576094
http://dx.doi.org/10.3390/ijms22189933