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Fast activation maximization for molecular sequence design

BACKGROUND: Optimization of DNA and protein sequences based on Machine Learning models is becoming a powerful tool for molecular design. Activation maximization offers a simple design strategy for differentiable models: one-hot coded sequences are first approximated by a continuous representation, w...

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Detalles Bibliográficos
Autores principales: Linder, Johannes, Seelig, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527647/
https://www.ncbi.nlm.nih.gov/pubmed/34670493
http://dx.doi.org/10.1186/s12859-021-04437-5