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Dose-Sparing Intradermal DTaP-sIPV Immunization With a Hollow Microneedle Leads to Superior Immune Responses
Dose-sparing intradermal (ID) vaccination may induce the same immune responses as intramuscular (IM) vaccination, which can increase vaccine supplies and save costs. In this study, rats were immunized with fractional-dose of Sabin-derived IPV combined with diphtheria-tetanus-acellular pertussis vacc...
Autores principales: | Zuo, Weilun, Li, Jingyan, Jiang, Wenwen, Zhang, Mengyao, Ma, Yan, Gu, Qin, Wang, Xiaoyu, Cai, Lukui, Shi, Li, Sun, Mingbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573275/ https://www.ncbi.nlm.nih.gov/pubmed/34759909 http://dx.doi.org/10.3389/fmicb.2021.757375 |
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