A Novel Hydroxamic Acid-Based Curcumin Derivative as Potent Histone Deacetylase Inhibitor for the Treatment of Glioblastoma

Glioblastoma (GBM) is one of the most common primary and deadliest malignant brain tumor with chemoresistance and poor prognosis. There is a lack of effective chemotherapeutic drug for the treatment of GBM. In this work, we reported the preparation of a histone deacetylase (HDAC) inhibitor, DMC-HA,...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Shi, Lei, Wang, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602566/
https://www.ncbi.nlm.nih.gov/pubmed/34804949
http://dx.doi.org/10.3389/fonc.2021.756817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602566/
https://www.ncbi.nlm.nih.gov/pubmed/34804949
http://dx.doi.org/10.3389/fonc.2021.756817

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