Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case
Mucinous adenocarcinomas of the appendix are rare and often present as a suspected appendicitis. Diagnostic work-up encompasses colonoscopy, tissue biopsy, CT scan, and a multidisciplinary team input. Management involves surgery, hyperthermic intraperitoneal chemotherapy, and adjuvant chemotherapy....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648134/ https://www.ncbi.nlm.nih.gov/pubmed/34900502 http://dx.doi.org/10.7759/cureus.20157 |
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author | Vyas, Nirav Dornseifer, Mamun Nair, Manoj |
author_facet | Vyas, Nirav Dornseifer, Mamun Nair, Manoj |
author_sort | Vyas, Nirav |
collection | PubMed |
description | Mucinous adenocarcinomas of the appendix are rare and often present as a suspected appendicitis. Diagnostic work-up encompasses colonoscopy, tissue biopsy, CT scan, and a multidisciplinary team input. Management involves surgery, hyperthermic intraperitoneal chemotherapy, and adjuvant chemotherapy. Our patient was known to be human immunodeficiency virus (HIV) positive; therefore, careful consideration had to be taken in starting adjuvant chemotherapy as there were concerns of drug interactions and further immunosuppression. Despite all these challenges the patient has had an excellent outcome with no evidence of recurrence or distant disease. |
format | Online Article Text |
id | pubmed-8648134 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-86481342021-12-10 Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case Vyas, Nirav Dornseifer, Mamun Nair, Manoj Cureus General Surgery Mucinous adenocarcinomas of the appendix are rare and often present as a suspected appendicitis. Diagnostic work-up encompasses colonoscopy, tissue biopsy, CT scan, and a multidisciplinary team input. Management involves surgery, hyperthermic intraperitoneal chemotherapy, and adjuvant chemotherapy. Our patient was known to be human immunodeficiency virus (HIV) positive; therefore, careful consideration had to be taken in starting adjuvant chemotherapy as there were concerns of drug interactions and further immunosuppression. Despite all these challenges the patient has had an excellent outcome with no evidence of recurrence or distant disease. Cureus 2021-12-04 /pmc/articles/PMC8648134/ /pubmed/34900502 http://dx.doi.org/10.7759/cureus.20157 Text en Copyright © 2021, Vyas et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | General Surgery Vyas, Nirav Dornseifer, Mamun Nair, Manoj Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case |
title | Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case |
title_full | Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case |
title_fullStr | Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case |
title_full_unstemmed | Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case |
title_short | Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case |
title_sort | mucinous adenocarcinoma of the appendix: the challenges of managing a complex surgical case |
topic | General Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648134/ https://www.ncbi.nlm.nih.gov/pubmed/34900502 http://dx.doi.org/10.7759/cureus.20157 |
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