Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case

Mucinous adenocarcinomas of the appendix are rare and often present as a suspected appendicitis. Diagnostic work-up encompasses colonoscopy, tissue biopsy, CT scan, and a multidisciplinary team input. Management involves surgery, hyperthermic intraperitoneal chemotherapy, and adjuvant chemotherapy....

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Autores principales: Vyas, Nirav, Dornseifer, Mamun, Nair, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648134/
https://www.ncbi.nlm.nih.gov/pubmed/34900502
http://dx.doi.org/10.7759/cureus.20157
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author Vyas, Nirav
Dornseifer, Mamun
Nair, Manoj
author_facet Vyas, Nirav
Dornseifer, Mamun
Nair, Manoj
author_sort Vyas, Nirav
collection PubMed
description Mucinous adenocarcinomas of the appendix are rare and often present as a suspected appendicitis. Diagnostic work-up encompasses colonoscopy, tissue biopsy, CT scan, and a multidisciplinary team input. Management involves surgery, hyperthermic intraperitoneal chemotherapy, and adjuvant chemotherapy. Our patient was known to be human immunodeficiency virus (HIV) positive; therefore, careful consideration had to be taken in starting adjuvant chemotherapy as there were concerns of drug interactions and further immunosuppression. Despite all these challenges the patient has had an excellent outcome with no evidence of recurrence or distant disease.
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spelling pubmed-86481342021-12-10 Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case Vyas, Nirav Dornseifer, Mamun Nair, Manoj Cureus General Surgery Mucinous adenocarcinomas of the appendix are rare and often present as a suspected appendicitis. Diagnostic work-up encompasses colonoscopy, tissue biopsy, CT scan, and a multidisciplinary team input. Management involves surgery, hyperthermic intraperitoneal chemotherapy, and adjuvant chemotherapy. Our patient was known to be human immunodeficiency virus (HIV) positive; therefore, careful consideration had to be taken in starting adjuvant chemotherapy as there were concerns of drug interactions and further immunosuppression. Despite all these challenges the patient has had an excellent outcome with no evidence of recurrence or distant disease. Cureus 2021-12-04 /pmc/articles/PMC8648134/ /pubmed/34900502 http://dx.doi.org/10.7759/cureus.20157 Text en Copyright © 2021, Vyas et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Vyas, Nirav
Dornseifer, Mamun
Nair, Manoj
Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case
title Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case
title_full Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case
title_fullStr Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case
title_full_unstemmed Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case
title_short Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case
title_sort mucinous adenocarcinoma of the appendix: the challenges of managing a complex surgical case
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648134/
https://www.ncbi.nlm.nih.gov/pubmed/34900502
http://dx.doi.org/10.7759/cureus.20157
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