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Mapping yeast mitotic 5′ resection at base resolution reveals the sequence and positional dependence of nucleases in vivo
Resection of the 5′-terminated strand at DNA double-strand breaks (DSBs) is the critical regulated step in the transition to homologous recombination. Recent studies have described a multi-step model of DSB resection where endonucleolytic cleavage mediated by Mre11 and Sae2 leads to further degradat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682756/ https://www.ncbi.nlm.nih.gov/pubmed/34263309 http://dx.doi.org/10.1093/nar/gkab597 |