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Mapping yeast mitotic 5′ resection at base resolution reveals the sequence and positional dependence of nucleases in vivo

Resection of the 5′-terminated strand at DNA double-strand breaks (DSBs) is the critical regulated step in the transition to homologous recombination. Recent studies have described a multi-step model of DSB resection where endonucleolytic cleavage mediated by Mre11 and Sae2 leads to further degradat...

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Detalles Bibliográficos
Autores principales: Bazzano, Dominic, Lomonaco, Stephanie, Wilson, Thomas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682756/
https://www.ncbi.nlm.nih.gov/pubmed/34263309
http://dx.doi.org/10.1093/nar/gkab597