Cargando…

De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

Successful control of Mycobacterium tuberculosis (Mtb) infection by macrophages relies on immunometabolic reprogramming, where the role of fatty acids (FAs) remains poorly understood. Recent studies unraveled Mtb’s capacity to acquire saturated and monounsaturated FAs via the Mce1 importer. However,...

Descripción completa

Detalles Bibliográficos
Autores principales: Laval, Thomas, Pedró-Cos, Laura, Malaga, Wladimir, Guenin-Macé, Laure, Pawlik, Alexandre, Mayau, Véronique, Yahia-Cherbal, Hanane, Delos, Océane, Frigui, Wafa, Bertrand-Michel, Justine, Guilhot, Christophe, Demangel, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752091/
https://www.ncbi.nlm.nih.gov/pubmed/34951591
http://dx.doi.org/10.7554/eLife.71946