Polycationic HA/CpG Nanoparticles Induce Cross-Protective Influenza Immunity in Mice

[Image: see text] The intranasal (i.n.) route is an ideal vaccination approach for infectious respiratory diseases like influenza. Polycationic polyethylenimine (PEI) could form nanoscale complexes with negatively charged viral glycoproteins. Here we fabricated PEI-hemagglutinin (HA) and PEI-HA/CpG...

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Detalles Bibliográficos
Autores principales: Dong, Chunhong, Wang, Ye, Zhu, Wandi, Ma, Yao, Kim, Joo, Wei, Lai, Gonzalez, Gilbert X., Wang, Bao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832387/
https://www.ncbi.nlm.nih.gov/pubmed/35084819
http://dx.doi.org/10.1021/acsami.1c19192