Federated analysis of BRCA1 and BRCA2 variation in a Japanese cohort
More than 40% of the germline variants in ClinVar today are variants of uncertain significance (VUSs). These variants remain unclassified in part because the patient-level data needed for their interpretation is siloed. Federated analysis can overcome this problem by “bringing the code to the data”:...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975122/ https://www.ncbi.nlm.nih.gov/pubmed/35373174 http://dx.doi.org/10.1016/j.xgen.2022.100109 |