MiR-200c-3p targets SESN1 and represses the IL-6/AKT loop to prevent cholangiocyte activation and cholestatic liver fibrosis

Cholestasis causes ductular reaction in the liver where the reactive cholangiocytes not only proliferate but also gain a neuroendocrine-like phenotype, leading to inflammatory cell infiltration and extracellular matrix deposition and contributing to the development and progression of cholestatic liv...

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Detalles Bibliográficos
Autores principales: Song, Yongfeng, Tran, Melanie, Wang, Li, Shin, Dong-Ju, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042705/
https://www.ncbi.nlm.nih.gov/pubmed/34880414
http://dx.doi.org/10.1038/s41374-021-00710-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042705/
https://www.ncbi.nlm.nih.gov/pubmed/34880414
http://dx.doi.org/10.1038/s41374-021-00710-6

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