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Investigating the biosynthesis of Sch-642305 in the fungus Phomopsis sp. CMU-LMA

Sch-642305 is an unusual bicyclic 10-membered macrolide produced by the filamentous fungus Phomopsis sp. CMU-LMA for which no biosynthetic evidence exists. Here, we generate a draft genome sequence of the producing organism and discover the biosynthetic gene cluster responsible for formation of Sch-...

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Detalles Bibliográficos
Autores principales: Trenti, Francesco, Lebe, Karen E., Adelin, Emilie, Ouazzani, Jamal, Schotte, Carsten, Cox, Russell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055631/
https://www.ncbi.nlm.nih.gov/pubmed/35516937
http://dx.doi.org/10.1039/d0ra05311b