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One-Pot and Catalyst-Free Transformation of N-Protected 1-Amino-1-Ethoxyalkylphosphonates into Bisphosphonic Analogs of Protein and Non-Protein α-Amino Acids

Herein, we describe the development of one-pot transformation of α-ethoxy derivatives of phosphorus analogs of protein and non-protein α-amino acids into biologically important N-protected 1-aminobisphosphonates. The proposed strategy, based on the three-component reaction of 1-(N-acylamino)-1-ethox...

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Detalles Bibliográficos
Autores principales: Kuźnik, Anna, Kozicka, Dominika, Hawranek, Wioleta, Socha, Karolina, Erfurt, Karol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182278/
https://www.ncbi.nlm.nih.gov/pubmed/35684508
http://dx.doi.org/10.3390/molecules27113571