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Daisaikoto improves fatty liver and obesity in melanocortin-4 receptor gene-deficient mice via the activation of brown adipose tissue
Melanocortin 4 receptor gene-knockout (MC4R-KO) mice are known to develop obesity with a high-fat diet. Meanwhile, daisaikoto, one of Kampo medicines, is a drug that is expected to have therapeutic effects on obesity. Here, we report the efficacy of daisaikoto in MC4R-KO mice. Eight-week-old MC4R-KO...
Autores principales: | Morita, Shinichi, Sakamaki, Akira, Koyama, Kyutaro, Shibata, Osamu, Owaki, Takashi, Oda, Chiyumi, Kimura, Atsushi, Nakaya, Taiki, Ohbuchi, Katsuya, Nahata, Miwa, Fujitsuka, Naoki, Sakai, Norihiro, Abe, Hiroyuki, Kamimura, Kenya, Terai, Shuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203505/ https://www.ncbi.nlm.nih.gov/pubmed/35710868 http://dx.doi.org/10.1038/s41598-022-14371-y |
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