Upregulation of Atypical Cadherin FAT1 Promotes an Immunosuppressive Tumor Microenvironment via TGF-β

FAT atypical cadherin 1 (FAT1) promotes glioblastoma (GBM) by promoting protumorigenic inflammatory cytokine expression in tumor cells. However, tumors also have an immunosuppressive microenvironment maintained by mediators such as transforming growth factor (TGF)-β cytokines. Here, we have studied...

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Detalles Bibliográficos
Autores principales: Irshad, Khushboo, Srivastava, Chitrangda, Malik, Nargis, Arora, Manvi, Gupta, Yakhlesh, Goswami, Sanjeev, Sarkar, Chitra, Suri, Vaishali, Mahajan, Swati, Gupta, Deepak Kumar, Suri, Ashish, Chattopadhyay, Parthaprasad, Sinha, Subrata, Chosdol, Kunzang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205206/
https://www.ncbi.nlm.nih.gov/pubmed/35720420
http://dx.doi.org/10.3389/fimmu.2022.813888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205206/
https://www.ncbi.nlm.nih.gov/pubmed/35720420
http://dx.doi.org/10.3389/fimmu.2022.813888

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