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G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C–T base-pair

The Caenorhabditis elegans model has greatly contributed to the understanding of the role of G-quadruplexes in genomic instability. The GGCTTA repeats of the C. elegans telomeres resemble the GGGTTA repeats of the human telomeres. However, the comparison of telomeric sequences (Homo sapiens, Tetrahy...

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Detalles Bibliográficos
Autores principales: Marquevielle, Julien, De Rache, Aurore, Vialet, Brune, Morvan, Estelle, Mergny, Jean-Louis, Amrane, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262591/
https://www.ncbi.nlm.nih.gov/pubmed/35736226
http://dx.doi.org/10.1093/nar/gkac523