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A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand

Heat shock protein-90 (Hsp90) chaperone machinery is involved in the stability and activity of its client proteins. The chaperone function of Hsp90 is regulated by co-chaperones and post-translational modifications. Although structural evidence exists for Hsp90 interaction with clients, our understa...

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Detalles Bibliográficos
Autores principales: Backe, Sarah J., Sager, Rebecca A., Regan, Bethany R., Sit, Julian, Major, Lauren A., Bratslavsky, Gennady, Woodford, Mark R., Bourboulia, Dimitra, Mollapour, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306012/
https://www.ncbi.nlm.nih.gov/pubmed/35830801
http://dx.doi.org/10.1016/j.celrep.2022.111039