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Fabrication, In Vitro and In Vivo Evaluation of Non-Ordered Mesoporous Silica-Based Ternary Solid Dispersions for Enhanced Solubility of Flurbiprofen

The aim of this study was to improve the solubility and prevent the ulcerogenic effect of flurbiprofen. Initially, binary and ternary solid dispersions (BSDs and TSDs) of flurbiprofen were prepared by using non-ordered mesoporous silica and gelucire. After preformulation testing (solubility, flow pr...

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Detalles Bibliográficos
Autores principales: Munir, Muhammad Usman, Ikraam, Mahnoor, Nadeem, Muhammad, Khalid, Syed Haroon, Asghar, Sajid, Khalid, Ikrima, Irfan, Muhammad, Islam, Nayyer, Ajaz, Nyla, Khan, Ikram Ullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324605/
https://www.ncbi.nlm.nih.gov/pubmed/35890153
http://dx.doi.org/10.3390/ph15070856