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Systematic evaluation of tumor microenvironment and construction of a machine learning model to predict prognosis and immunotherapy efficacy in triple-negative breast cancer based on data mining and sequencing validation

Background: The role of the tumor microenvironment (TME) in predicting prognosis and therapeutic efficacy has been demonstrated. Nonetheless, no systematic studies have focused on TME patterns or their function in the effectiveness of immunotherapy in triple-negative breast cancer. Methods: We compr...

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Detalles Bibliográficos
Autores principales: Gou, Qiheng, Liu, Zijian, Xie, Yuxin, Deng, Yulan, Ma, Ji, Li, Jiangping, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548553/
https://www.ncbi.nlm.nih.gov/pubmed/36225561
http://dx.doi.org/10.3389/fphar.2022.995555