RGS11-CaMKII complex mediated redox control attenuates chemotherapy-induced cardiac fibrosis

Dose limiting cardiotoxicity remains a major limiting factor in the clinical use of several cancer chemotherapeutics including anthracyclines and the antimetabolite 5-fluorouracil (5-FU). Prior work has demonstrated that chemotherapeutics increase expression of R7 family regulator of G protein signa...

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Detalles Bibliográficos
Autores principales: Das, Kiran, Basak, Madhuri, Mahata, Tarun, Kumar, Manish, Kumar, Dinesh, Biswas, Sayan, Chatterjee, Suvro, Moniruzzaman, Mahammed, Saha, Nimai Chandra, Mondal, Kausik, Kumar, Pranesh, Das, Priyadip, Stewart, Adele, Maity, Biswanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557029/
https://www.ncbi.nlm.nih.gov/pubmed/36228439
http://dx.doi.org/10.1016/j.redox.2022.102487