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Correlation of Yes-Associated Protein 1 with Stroma Type and Tumor Stiffness in Hormone-Receptor Positive Breast Cancer
SIMPLE SUMMARY: YAP1 is an oncogene that can be activated by matrix stiffness, as it can act as a mechanotransducer. So far, only in vitro studies regarding YAP1 activation and matrix stiffness are present. We confirmed the activation of YAP1 in breast cancer using human breast cancer tissue and imm...
Autores principales: | Lee, Yangkyu, Bae, Soong June, Eun, Na Lae, Ahn, Sung Gwe, Jeong, Joon, Cha, Yoon Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599900/ https://www.ncbi.nlm.nih.gov/pubmed/36291755 http://dx.doi.org/10.3390/cancers14204971 |
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