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IGF2BP3 promotes progression of gallbladder carcinoma by stabilizing KLK5 mRNA in N(6)-methyladenosine-dependent binding

BACKGROUND: Recent studies have reported that IGF2BP3 is linked to the pathogenesis of various malignancies. Since IGF2BP3 is associated with poor outcomes of gallbladder carcinoma (GBC), we aimed to explore the association between its N(6)-methyladenosine (m6A) RNA methylation and GBC progression....

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Detalles Bibliográficos
Autores principales: Zhang, Junzhe, Yang, Kaini, Bu, Junfeng, Yan, Jiayan, Hu, Xiaoqiang, Liu, Ke, Gao, Si, Tang, Shuibin, Gao, Lili, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606626/
https://www.ncbi.nlm.nih.gov/pubmed/36313631
http://dx.doi.org/10.3389/fonc.2022.1035871