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Human Papillomavirus Infection during Pregnancy and Childhood: A Comprehensive Review

Human papillomavirus (HPV), the most prevalent sexually transmitted disease worldwide, is the causative agent for several genital and oropharyngeal cancers and a suspected agent for many malignancies. HPV is associated with several adverse health outcomes during pregnancy. Infants are also at risk o...

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Detalles Bibliográficos
Autores principales: Ardekani, Ali, Taherifard, Erfan, Mollalo, Abolfazl, Hemadi, Emadeddin, Roshanshad, Amirhossein, Fereidooni, Reza, Rouholamin, Safoura, Rezaeinejad, Mahroo, Farid-Mojtahedi, Maryam, Razavi, Maryam, Rostami, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607260/
https://www.ncbi.nlm.nih.gov/pubmed/36296208
http://dx.doi.org/10.3390/microorganisms10101932
Descripción
Sumario:Human papillomavirus (HPV), the most prevalent sexually transmitted disease worldwide, is the causative agent for several genital and oropharyngeal cancers and a suspected agent for many malignancies. HPV is associated with several adverse health outcomes during pregnancy. Infants are also at risk of HPV infection via different transmission routes: vertically from an infected mother and horizontally through sexual or non-sexual contact with infected individuals. Several HPV manifestations have been identified during childhood, ranging from common skin infections to severe complications such as juvenile recurrent respiratory papillomatosis. This review aims to provide a comprehensive overview of the epidemiology, manifestations, and treatment strategies of HPV infection during pregnancy and childhood. Moreover, we underline the role of vaccination in preventing complications.