Construction and application of an efficient dual-base editing platform for Bacillus subtilis evolution employing programmable base conversion

The functionally evolved bacterial chassis is of great importance to manufacture a group of assorted high value-added chemicals, from small molecules to biologically active macromolecules. However, the current evolution frameworks are less efficienct in generating in vivo genomic diversification bec...

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Detalles Bibliográficos
Autores principales: Hao, Wenliang, Cui, Wenjing, Suo, Feiya, Han, Laichuang, Cheng, Zhongyi, Zhou, Zhemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749471/
https://www.ncbi.nlm.nih.gov/pubmed/36545152
http://dx.doi.org/10.1039/d2sc05824c