Intracellular IFN-γ and IL-4 levels of CD4 + and CD8 + T cells in the peripheral blood of naturally infected (Leishmania infantum) symptomatic dogs before and following a 4-week treatment with miltefosine and allopurinol: a double-blinded, controlled and cross-sectional study

BACKGROUND: Canine leishmaniosis (CanL) is a systemic disease caused by the protozoan parasite Leishmania infantum with a wide spectrum of clinical signs, with cutaneous, ocular, renal and lymphoreactive conditions prevailing in the clinical setting. The immune system plays a pivotal role in the evo...

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Detalles Bibliográficos
Autores principales: Matralis, Dimitrios T., Koutinas, Alexander F., Papadogiannaki, Ioanna E., Papadopoulos, Elias G., Papadogiannakis, Emmanouil I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878989/
https://www.ncbi.nlm.nih.gov/pubmed/36703227
http://dx.doi.org/10.1186/s13028-023-00666-1