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Fast cycling of intermittent hypoxia in a physiomimetic 3D environment: A novel tool for the study of the parenchymal effects of sleep apnea

Background: Patients with obstructive sleep apnea (OSA) experience recurrent hypoxemic events with a frequency sometimes exceeding 60 events/h. These episodic events induce downstream transient hypoxia in the parenchymal tissue of all organs, thereby eliciting the pathological consequences of OSA. W...

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Detalles Bibliográficos
Autores principales: Jurado, Alicia, Ulldemolins, Anna, Lluís, Helena, Gasull, Xavier, Gavara, Núria, Sunyer, Raimon, Otero, Jorge, Gozal, David, Almendros, Isaac, Farré, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879064/
https://www.ncbi.nlm.nih.gov/pubmed/36712654
http://dx.doi.org/10.3389/fphar.2022.1081345