IFNα and 5-Aza-2’-deoxycytidine combined with a dendritic-cell targeting DNA vaccine alter tumor immune cell infiltration in the B16F10 melanoma model

INTRODUCTION: DNA vaccines containing a fusion of the gene encoding chemokine MIP-3α (CCL20), the ligand for CCR6 on immature dendritic cells (DCs), to melanoma-associated antigen genes have enhanced anti-tumor immunity and efficacy compared to those lacking the chemokine gene. Previous work has sho...

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Detalles Bibliográficos
Autores principales: Gordy, James T., Sandhu, Avinaash K., Fessler, Kaitlyn, Luo, Kun, Kapoor, Aakanksha R., Ayeh, Samuel K., Hui, Yinan, Schill, Courtney, Chen, Fengyixin, Wang, Tianyin, Karanika, Styliani, Sunshine, Joel C., Karakousis, Petros C., Markham, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892704/
https://www.ncbi.nlm.nih.gov/pubmed/36741387
http://dx.doi.org/10.3389/fimmu.2022.1074644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892704/
https://www.ncbi.nlm.nih.gov/pubmed/36741387
http://dx.doi.org/10.3389/fimmu.2022.1074644

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