HDAC8 Deacetylates HIF-1α and Enhances Its Protein Stability to Promote Tumor Growth and Migration in Melanoma

SIMPLE SUMMARY: Melanoma is the deadliest form of skin cancer, with its incidence increasing significantly over the past few decades. The hypoxic microenvironment of melanoma gives rise to the expression of hypoxia-inducible factor-1 (HIF-1), which mediates various signaling pathways that lead to me...

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Detalles Bibliográficos
Autores principales: Kim, Ji Yoon, Cho, Hayoung, Yoo, Jung, Kim, Go Woon, Jeon, Yu Hyun, Lee, Sang Wu, Kwon, So Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953989/
https://www.ncbi.nlm.nih.gov/pubmed/36831463
http://dx.doi.org/10.3390/cancers15041123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953989/
https://www.ncbi.nlm.nih.gov/pubmed/36831463
http://dx.doi.org/10.3390/cancers15041123

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