The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery

Energy-dependent protein degradation by the AAA+ ClpXP protease helps maintain protein homeostasis in bacteria and eukaryotic organelles of bacterial origin. In Escherichia coli and many other proteobacteria, the SspB adaptor assists ClpXP in degrading ssrA-tagged polypeptides produced as a conseque...

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Detalles Bibliográficos
Autores principales: Ghanbarpour, Alireza, Fei, Xue, Baker, Tania A., Davis, Joseph H., Sauer, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963277/
https://www.ncbi.nlm.nih.gov/pubmed/36730206
http://dx.doi.org/10.1073/pnas.2219044120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963277/
https://www.ncbi.nlm.nih.gov/pubmed/36730206
http://dx.doi.org/10.1073/pnas.2219044120

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