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Synapses, predictions, and prediction errors: A neocortical computational study of MDD using the temporal memory algorithm of HTM
INTRODUCTION: Synapses and spines play a significant role in major depressive disorder (MDD) pathophysiology, recently highlighted by the rapid antidepressant effect of ketamine and psilocybin. According to the Bayesian brain and interoception perspectives, MDD is formalized as being stuck in affect...
Autores principales: | Sherif, Mohamed A., Khalil, Mostafa Z., Shukla, Rammohan, Brown, Joshua C., Carpenter, Linda L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995817/ https://www.ncbi.nlm.nih.gov/pubmed/36911109 http://dx.doi.org/10.3389/fpsyt.2023.976921 |
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