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Exosome/metformin-loaded self-healing conductive hydrogel rescues microvascular dysfunction and promotes chronic diabetic wound healing by inhibiting mitochondrial fission
Chronic diabetic wounds remain a globally recognized clinical challenge. They occur due to high concentrations of reactive oxygen species and vascular function disorders. A promising strategy for diabetic wound healing is the delivery of exosomes, comprising bioactive dressings. Metformin activates...
Autores principales: | Zhang, Yue, Li, Meng, Wang, Yunchuan, Han, Fei, Shen, Kuo, Luo, Liang, Li, Yan, Jia, Yanhui, Zhang, Jian, Cai, Weixia, Wang, Kejia, Zhao, Ming, Wang, Jing, Gao, Xiaowen, Tian, Chenyang, Guo, Baolin, Hu, Dahai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027478/ https://www.ncbi.nlm.nih.gov/pubmed/36950152 http://dx.doi.org/10.1016/j.bioactmat.2023.01.020 |
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