Interaction between dual specificity phosphatase-1 and cullin-1 attenuates alcohol-related liver disease by restoring p62-mediated mitophagy

Besides abstinence, no effective treatment exists for alcohol-related liver disease (ALD), a dreaded consequence of alcohol abuse. In this study, we assessed the roles on ALD of dual specificity phosphatase-1 (DUSP1), an hepatoprotective enzyme, and Cullin-1 (CUL1), a member of the E3 ubiquitin liga...

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Detalles Bibliográficos
Autores principales: Li, Ruibing, Dai, Zhe, Liu, Xiaoman, Wang, Chunling, Huang, Jia, Xin, Ting, Tong, Ying, Wang, Yijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10092755/
https://www.ncbi.nlm.nih.gov/pubmed/37063418
http://dx.doi.org/10.7150/ijbs.81447