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Circuit Topology Approach for the Comparative Analysis of Intrinsically Disordered Proteins

[Image: see text] Intrinsically disordered proteins (IDPs) lack a stable native conformation, making it challenging to characterize their structure and dynamics. Key topological motifs with fundamental biological relevance are often hidden in the conformational noise, eluding detection. Here, we dev...

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Detalles Bibliográficos
Autores principales: Scalvini, Barbara, Sheikhhassani, Vahid, van de Brug, Nadine, Heling, Laurens W. H. J., Schmit, Jeremy D., Mashaghi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131221/
https://www.ncbi.nlm.nih.gov/pubmed/37026598
http://dx.doi.org/10.1021/acs.jcim.3c00391