VPA improves ferroptosis in tubular epithelial cells after cisplatin-induced acute kidney injury

Background: As a novel non-apoptotic cell death, ferroptosis has been reported to play a crucial role in acute kidney injury (AKI), especially cisplatin-induced AKI. Valproic acid (VPA), an inhibitor of histone deacetylase (HDAC) 1 and 2, is used as an antiepileptic drug. Consistent with our data, a...

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Detalles Bibliográficos
Autores principales: Li, Yan, Li, Ke, Zhao, Weihao, Wang, Haodong, Xue, Xiaodong, Chen, Xianghui, Li, Wantao, Xu, Peihao, Wang, Kexin, Liu, Pengfei, Tian, Xuefei, Fu, Rongguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155836/
https://www.ncbi.nlm.nih.gov/pubmed/37153759
http://dx.doi.org/10.3389/fphar.2023.1147772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155836/
https://www.ncbi.nlm.nih.gov/pubmed/37153759
http://dx.doi.org/10.3389/fphar.2023.1147772

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