Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring

Plasma cell-free DNA (cfDNA) is a noninvasive biomarker for cell death of all organs. Deciphering the tissue origin of cfDNA can reveal abnormal cell death because of diseases, which has great clinical potential in disease detection and monitoring. Despite the great promise, the sensitive and accura...

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Detalles Bibliográficos
Autores principales: Li, Shuo, Zeng, Weihua, Ni, Xiaohui, Liu, Qiao, Li, Wenyuan, Stackpole, Mary L., Zhou, Yonggang, Gower, Arjan, Krysan, Kostyantyn, Ahuja, Preeti, Lu, David S., Raman, Steven S., Hsu, William, Aberle, Denise R., Magyar, Clara E., French, Samuel W., Han, Steven-Huy B., Garon, Edward B., Agopian, Vatche G., Wong, Wing Hung, Dubinett, Steven M., Zhou, Xianghong Jasmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334733/
https://www.ncbi.nlm.nih.gov/pubmed/37399400
http://dx.doi.org/10.1073/pnas.2305236120

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