Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis

Human schistosomiasis is a neglected tropical disease caused by Schistosoma mansoni, S. haematobium, and S. japonicum. Praziquantel (PZQ) is the method of choice for treatment. Due to constant selection pressure, there is an urgent need for new therapies for schistosomiasis. Previous treatment of S....

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Detalles Bibliográficos
Autores principales: Alwan, Sevan N., Taylor, Alexander B., Rhodes, Jayce, Tidwell, Michael, McHardy, Stanton F., LoVerde, Philip T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359000/
https://www.ncbi.nlm.nih.gov/pubmed/37428793
http://dx.doi.org/10.1371/journal.ppat.1011018