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Temporal Pattern of the Emergence of a Mutant Virus Escaping Cross-Immunity and Stochastic Extinction Within a Host

A high mutation rate of the RNA virus results in the emergence of novel mutants that may escape the immunity activated by the original (wild-type) strain. However, many of them go extinct because of the stochasticity due to the small initial number of infected cells. In a previous paper, we studied...

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Detalles Bibliográficos
Autores principales: Hayashi, Rena, Iwasa, Yoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382422/
https://www.ncbi.nlm.nih.gov/pubmed/37507538
http://dx.doi.org/10.1007/s11538-023-01184-x