O-methyltransferase-like enzyme catalyzed diazo installation in polyketide biosynthesis

Diazo compounds are rare natural products possessing various biological activities. Kinamycin and lomaiviticin, two diazo natural products featured by the diazobenzofluorene core, exhibit exceptional potency as chemotherapeutic agents. Despite the extensive studies on their biosynthetic gene cluster...

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Detalles Bibliográficos
Autores principales: Zhao, Yuchun, Liu, Xiangyang, Xiao, Zhihong, Zhou, Jie, Song, Xingyu, Wang, Xiaozheng, Hu, Lijun, Wang, Ying, Sun, Peng, Wang, Wenning, He, Xinyi, Lin, Shuangjun, Deng, Zixin, Pan, Lifeng, Jiang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477347/
https://www.ncbi.nlm.nih.gov/pubmed/37666836
http://dx.doi.org/10.1038/s41467-023-41062-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477347/
https://www.ncbi.nlm.nih.gov/pubmed/37666836
http://dx.doi.org/10.1038/s41467-023-41062-7

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