Loss of ATP-sensitive channel expression and function decreases opioid sensitivity in a mouse model of type 2 diabetes

During diabetes, β-cell dysfunction due to loss of potassium channels sensitive to ATP, known as K(ATP) channels occurs progressively over time contributing to hyperglycemia. K(ATP) channels are additionally present in the central and peripheral nervous systems and are downstream targets of opioid r...

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Detalles Bibliográficos
Autores principales: Fisher, Cole, Johnson, Kayla, Moore, Madelyn, Sadrati, Amir, Janecek, Jody L., Graham, Melanie L., Klein, Amanda H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508758/
https://www.ncbi.nlm.nih.gov/pubmed/37732180
http://dx.doi.org/10.1101/2023.09.06.556526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508758/
https://www.ncbi.nlm.nih.gov/pubmed/37732180
http://dx.doi.org/10.1101/2023.09.06.556526

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