RAP80 phase separation at DNA double-strand break promotes BRCA1 recruitment

RAP80 has been characterized as a component of the BRCA1-A complex and is responsible for the recruitment of BRCA1 to DNA double-strand breaks (DSBs). However, we and others found that the recruitment of RAP80 and BRCA1 were not absolutely temporally synchronized, indicating that other mechanisms, a...

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Detalles Bibliográficos
Autores principales: Qin, Caolitao, Wang, Yun-Long, Zhou, Jin-Ying, Shi, Jie, Zhao, Wan-Wen, Zhu, Ya-Xi, Bai, Shao-Mei, Feng, Li-Li, Bie, Shu-Ying, Zeng, Bing, Zheng, Jian, Zeng, Guang-Dong, Feng, Wei-Xing, Wan, Xiang-Bo, Fan, Xin-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570032/
https://www.ncbi.nlm.nih.gov/pubmed/37638744
http://dx.doi.org/10.1093/nar/gkad686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570032/
https://www.ncbi.nlm.nih.gov/pubmed/37638744
http://dx.doi.org/10.1093/nar/gkad686

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