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SARS-CoV-2 spike protein S1 activates Cx43 hemichannels and disturbs intracellular Ca(2+) dynamics

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the ongoing coronavirus disease 2019 (COVID-19). An aspect of high uncertainty is whether the SARS-CoV-2 per se or the systemic inflammation induced by viral infection directly affects cellular function and survival in d...

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Detalles Bibliográficos
Autores principales: Prieto-Villalobos, Juan, Lucero, Claudia M., Rovegno, Maximiliano, Gómez, Gonzalo I., Retamal, Mauricio A., Orellana, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598968/
https://www.ncbi.nlm.nih.gov/pubmed/37876016
http://dx.doi.org/10.1186/s40659-023-00468-9