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CENTRE: a gradient boosting algorithm for Cell-type-specific ENhancer-Target pREdiction

MOTIVATION: Identifying target promoters of active enhancers is a crucial step for realizing gene regulation and deciphering phenotypes and diseases. Up to now, several computational methods were developed to predict enhancer gene interactions, but they require either many epigenomic and transcripto...

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Detalles Bibliográficos
Autores principales: Rapakoulia, Trisevgeni, Lopez Ruiz De Vargas, Sara, Omgba, Persia Akbari, Laupert, Verena, Ulitsky, Igor, Vingron, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666202/
https://www.ncbi.nlm.nih.gov/pubmed/37982748
http://dx.doi.org/10.1093/bioinformatics/btad687