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SnoN expression is differently regulated in microsatellite unstable compared with microsatellite stable colorectal cancers

BACKGROUND: SnoN is an important regulator of the transforming growth factor beta (TGFβ) signalling pathway and has been shown to exhibit both tumour promotion and suppression activity. METHODS: To further explore the role of this complex molecule in colorectal tumorigenesis, we examined 52 paired n...

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Detalles Bibliográficos
Autores principales: Chia, June A, Simms, Lisa A, Cozzi, Sarah-Jane, Young, Joanne, Jass, Jeremy R, Walsh, Michael D, Spring, Kevin J, Leggett, Barbara A, Whitehall, Vicki LJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1633742/
https://www.ncbi.nlm.nih.gov/pubmed/17062133
http://dx.doi.org/10.1186/1471-2407-6-252