Functional and structural characterization of the integrase from the prototype foamy virus

Establishment of the stable provirus is an essential step in retroviral replication, orchestrated by integrase (IN), a virus-derived enzyme. Until now, available structural information was limited to the INs of human immunodeficiency virus type 1 (HIV-1), avian sarcoma virus (ASV) and their close or...

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Detalles Bibliográficos
Autores principales: Valkov, Eugene, Gupta, Saumya Shree, Hare, Stephen, Helander, Anna, Roversi, Pietro, McClure, Myra, Cherepanov, Peter
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615609/
https://www.ncbi.nlm.nih.gov/pubmed/19036793
http://dx.doi.org/10.1093/nar/gkn938