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Modeling the Quantitative Specificity of DNA-Binding Proteins from Example Binding Sites

BACKGROUND: The binding of transcription factors to their respective DNA sites is a key component of every regulatory network. Predictions of transcription factor binding sites are usually based on models for transcription factor specificity. These models, in turn, are often based on examples of kno...

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Detalles Bibliográficos
Autores principales: Homsi, Dana S. F., Gupta, Vineet, Stormo, Gary D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726951/
https://www.ncbi.nlm.nih.gov/pubmed/19707584
http://dx.doi.org/10.1371/journal.pone.0006736