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Interaction of E2 Glycoprotein with Heparan Sulfate Is Crucial for Cellular Infection of Sindbis Virus

Cell culture-adapted strains of Sindbis virus (SINV) initially attach to cells by the ability to interact with heparan sulfate (HS) through selective mutation for positively charged amino acid (aa) scattered in E2 glycoprotein (W. B. Klimstra, K. D. Ryman, and R. E. Johnston, J. Virol. 72: 7357–7366...

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Detalles Bibliográficos
Autores principales: Zhu, Wuyang, Wang, Lihua, Yang, Yiliang, Jia, Juan, Fu, Shihong, Feng, Yun, He, Ying, Li, Jin-Ping, Liang, Guodong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836379/
https://www.ncbi.nlm.nih.gov/pubmed/20300181
http://dx.doi.org/10.1371/journal.pone.0009656

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