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Hypusine-containing Protein eIF5A Promotes Translation Elongation

Translation elongation factors facilitate protein synthesis by the ribosome. Previous studies identified two universally conserved translation elongation factors EF-Tu/eEF1A and EF-G/eEF2 that deliver aminoacyl-tRNAs to the ribosome and promote ribosomal translocation, respectively(1). The factor eI...

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Detalles Bibliográficos
Autores principales: Saini, Preeti, Eyler, Daniel E., Green, Rachel, Dever, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140696/
https://www.ncbi.nlm.nih.gov/pubmed/19424157
http://dx.doi.org/10.1038/nature08034