Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants

Memory B cells (MBCs) and long-lived plasma cells (LLPCs) persist after clearance of infection, yet the specific and nonredundant role MBCs play in subsequent protection is unclear. After resolution of West Nile virus infection in mice, we demonstrate that LLPCs were specific for a single dominant n...

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Detalles Bibliográficos
Autores principales: Purtha, Whitney E., Tedder, Thomas F., Johnson, Syd, Bhattacharya, Deepta, Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244041/
https://www.ncbi.nlm.nih.gov/pubmed/22162833
http://dx.doi.org/10.1084/jem.20110740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244041/
https://www.ncbi.nlm.nih.gov/pubmed/22162833
http://dx.doi.org/10.1084/jem.20110740

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